148 research outputs found
On the stability of standing matter waves in a trap
We discuss excited Bose-condensed states and find the criterion of dynamical
stability of a kink-wise state, i.e., a standing matter wave with one nodal
plane perpendicular to the axis of a cylindrical trap. The dynamical stability
requires a strong radial confinement corresponding to the radial frequency
larger than the mean-field interparticle interaction. We address the question
of thermodynamic instability related to the presence of excitations with
negative energy.Comment: 4 pages, 3 figure
Moment of Inertia and Quadrupole Response Function of a Trapped Superfluid
We derive an explicit relationship between the moment of inertia and the
quadrupole response function of an interacting gas confined in a harmonic trap.
The relationship holds for both Bose and Fermi systems and is well suited to
reveal the effects of irrotationality of the superfluid motion. Recent
experimental results on the scissors mode are used to extract the value of the
moment of inertia of a trapped Bose gas and to point out the deviations from
the rigid value due to superfluidity.Comment: 6 page
The Frequency Dependence of Critical-velocity Behavior in Oscillatory Flow of Superfluid Helium-4 Through a 2-micrometer by 2-micrometer Aperture in a Thin Foil
The critical-velocity behavior of oscillatory superfluid Helium-4 flow
through a 2-micrometer by 2-micrometer aperture in a 0.1-micrometer-thick foil
has been studied from 0.36 K to 2.10 K at frequencies from less than 50 Hz up
to above 1880 Hz. The pressure remained less than 0.5 bar. In early runs during
which the frequency remained below 400 Hz, the critical velocity was a
nearly-linearly decreasing function of increasing temperature throughout the
region of temperature studied. In runs at the lowest frequencies, isolated 2 Pi
phase slips could be observed at the onset of dissipation. In runs with
frequencies higher than 400 Hz, downward curvature was observed in the decrease
of critical velocity with increasing temperature. In addition, above 500 Hz an
alteration in supercritical behavior was seen at the lower temperatures,
involving the appearance of large energy-loss events. These irregular events
typically lasted a few tens of half-cycles of oscillation and could involve
hundreds of times more energy loss than would have occurred in a single
complete 2 Pi phase slip at maximum flow. The temperatures at which this
altered behavior was observed rose with frequency, from ~ 0.6 K and below, at
500 Hz, to ~ 1.0 K and below, at 1880 Hz.Comment: 35 pages, 13 figures, prequel to cond-mat/050203
The glassy response of solid He-4 to torsional oscillations
We calculated the glassy response of solid He-4 to torsional oscillations
assuming a phenomenological glass model. Making only a few assumptions about
the distribution of glassy relaxation times in a small subsystem of otherwise
rigid solid He-4, we can account for the magnitude of the observed period shift
and concomitant dissipation peak in several torsion oscillator experiments. The
implications of the glass model for solid He-4 are threefold: (1) The dynamics
of solid He-4 is governed by glassy relaxation processes. (2) The distribution
of relaxation times varies significantly between different torsion oscillator
experiments. (3) The mechanical response of a torsion oscillator does not
require a supersolid component to account for the observed anomaly at low
temperatures, though we cannot rule out its existence.Comment: 9 pages, 4 figures, presented at QFS200
Threshold criterion for wetting at the triple point
Grand canonical simulations are used to calculate adsorption isotherms of
various classical gases on alkali metal and Mg surfaces. Ab initio adsorption
potentials and Lennard-Jones gas-gas interactions are used. Depending on the
system, the resulting behavior can be nonwetting for all temperatures studied,
complete wetting, or (in the intermediate case) exhibit a wetting transition.
An unusual variety of wetting transitions at the triple point is found in the
case of a specific adsorption potential of intermediate strength. The general
threshold for wetting near the triple point is found to be close to that
predicted with a heuristic model of Cheng et al. This same conclusion was drawn
in a recent experimental and simulation study of Ar on CO_2 by Mistura et al.
These results imply that a dimensionless wetting parameter w is useful for
predicting whether wetting behavior is present at and above the triple
temperature. The nonwetting/wetting crossover value found here is w circa 3.3.Comment: 15 pages, 8 figure
Simulations of Vortex Evolution and Phase Slip in Oscillatory Potential Flow of the Superfluid Component of Helium-4 Through an Aperture
The evolution of semicircular quantum vortex loops in oscillating potential
flow emerging from an aperture is simulated in some highly symmetrical cases.
As the frequency of potential flow oscillation increases, vortex loops that are
evolving so as eventually to cross all of the streamlines of potential flow are
drawn back toward the aperture when the flow reverses. As a result, the escape
size of the vortex loops, and hence the net energy transferred from potential
flow to vortex flow in such 2 Pi phase-slip events, decreases as the
oscillation frequency increases. Above some aperture-dependent and
flow-dependent threshold frequency, vortex loops are drawn back into the
aperture. Simulations are preformed using both radial potential flow and
oblate-spheroidal potential flow.Comment: 18 pages, 6 figures, sequel to cond-mat/050203
To wet or not to wet: that is the question
Wetting transitions have been predicted and observed to occur for various
combinations of fluids and surfaces. This paper describes the origin of such
transitions, for liquid films on solid surfaces, in terms of the gas-surface
interaction potentials V(r), which depend on the specific adsorption system.
The transitions of light inert gases and H2 molecules on alkali metal surfaces
have been explored extensively and are relatively well understood in terms of
the least attractive adsorption interactions in nature. Much less thoroughly
investigated are wetting transitions of Hg, water, heavy inert gases and other
molecular films. The basic idea is that nonwetting occurs, for energetic
reasons, if the adsorption potential's well-depth D is smaller than, or
comparable to, the well-depth of the adsorbate-adsorbate mutual interaction. At
the wetting temperature, Tw, the transition to wetting occurs, for entropic
reasons, when the liquid's surface tension is sufficiently small that the free
energy cost in forming a thick film is sufficiently compensated by the fluid-
surface interaction energy. Guidelines useful for exploring wetting transitions
of other systems are analyzed, in terms of generic criteria involving the
"simple model", which yields results in terms of gas-surface interaction
parameters and thermodynamic properties of the bulk adsorbate.Comment: Article accepted for publication in J. Low Temp. Phy
An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics
For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale. Analysis of clinicopathologic annotations for over 11,000 cancer patients in the TCGA program leads to the generation of TCGA Clinical Data Resource, which provides recommendations of clinical outcome endpoint usage for 33 cancer types
Metabolic diagnosis and medical prevention of calcium nephrolithiasis and its systemic manifestations: a consensus statement
Background: Recently published guidelines on the medical management of renal stone disease did not address relevant topics in the field of idiopathic calcium nephrolithiasis, which are important also for clinical research. Design: A steering committee identified 27 questions, which were proposed to a faculty of 44 experts in nephrolithiasis and allied fields. A systematic review of the literature was conducted and 5216 potentially relevant articles were selected; from these, 407 articles were deemed to provide useful scientific information. The Faculty, divided into working groups, analysed the relevant literature. Preliminary statements developed by each group were exhaustively discussed in plenary sessions and approved. Results: Statements were developed to inform clinicians on the identification of secondary forms of calcium nephrolithiasis and systemic complications; on the definition of idiopathic calcium nephrolithiasis; on the use of urinary tests of crystallization and of surgical observations during stone treatment in the management of these patients; on the identification of patients warranting preventive measures; on the role of fluid and nutritional measures and of drugs to prevent recurrent episodes of stones; and finally, on the cooperation between the urologist and nephrologist in the renal stone patients. Conclusions: This document has addressed idiopathic calcium nephrolithiasis from the perspective of a disease that can associate with systemic disorders, emphasizing the interplay needed between urologists and nephrologists. It is complementary to the American Urological Association and European Association of Urology guidelines. Future areas for research are identified
A connectome and analysis of the adult Drosophila central brain
The neural circuits responsible for animal behavior remain largely unknown. We summarize new methods and present the circuitry of a large fraction of the brain of the fruit fly Drosophila melanogaster. Improved methods include new procedures to prepare, image, align, segment, find synapses in, and proofread such large data sets. We define cell types, refine computational compartments, and provide an exhaustive atlas of cell examples and types, many of them novel. We provide detailed circuits consisting of neurons and their chemical synapses for most of the central brain. We make the data public and simplify access, reducing the effort needed to answer circuit questions, and provide procedures linking the neurons defined by our analysis with genetic reagents. Biologically, we examine distributions of connection strengths, neural motifs on different scales, electrical consequences of compartmentalization, and evidence that maximizing packing density is an important criterion in the evolution of the fly’s brain
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